Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - FAAH - AM 374

AM 374

CAS No. 86855-26-7

AM 374( —— )

Catalog No. M36258 CAS No. 86855-26-7

AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 Get Quote
10MG 64 Get Quote
25MG 127 Get Quote
50MG 204 Get Quote
100MG 295 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AM 374
  • Note
    Research use only, not for human use.
  • Brief Description
    AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM.
  • Description
    AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC50 value of 13 nM. AM 374 can be used for the research of neurological disease.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Adult male Sprague-Dawley rats with lever press training Dosage:20 μg Administration:Intraventricular (ICV) injection; 20 μg, once Result:Significantly reduced lever pressing when combined treatment with anandamide.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    FAAH
  • Recptor
    FAAH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    86855-26-7
  • Formula Weight
    308.5
  • Molecular Formula
    C16H33FO2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (324.15 mM; Ultrasonic )
  • SMILES
    CCCCCCCCCCCCCCCCS(F)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Deutsch DG, et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. Biochem Biophys Res Commun. 1997 Feb 3;231(1):217-21.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • PF 750

    PF 750 is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.

  • JNJ-42165279

    JNJ-42165279 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH) with IC50 of 70 nM for hFAAH.

  • SSR 411298

    SSR411298 is a highly selective, brain penetrant and orally-active inhibitor of FAAH with IC50 of 62.5 nM (mouse brain FAAH).

Sign In Join Free